Purpose: To evaluate the color alterations, flexural strength, and microhardness properties of two different 3D-printed permanent crown resins. Materials and Methods: Samples were produced from two different 3D-printed permanent crown resins: Group 1 (Saremco Crowntec, Saremco Dental) and Group 2 (P-crown V2, Senertek). Color changes (ΔE values), flexural strength, and Vickers hardness number (VHN) of the samples were calculated. Data were analyzed with Shapiro-Wilk normality test, independent t test, and Mann-Whitney U tests. The significance level was accepted as P < .05. Results: ΔE values for red wine were found to be significantly higher in Group 1 (6.43 ± 2.26; P < .001). The flexural strength values (MPa) of Group 1 were significantly higher than Group 2 in all three solutions (P < .001). There was no significant difference between the VHN values of the samples kept in wine and coffee solutions (P = .271; .827). Conclusions: 3D-printing resins are affected at different levels by coloring solutions. Microhardness and flexural strength of 3D-printed samples kept in different coloring agents are different. In the use of 3D-printing resins, product selection should be made by taking into account the individual factors such as the eating and drinking habits of the patient and the physical properties expected from the sample.