This report involves the retrospective evaluation of ITI implants placed by a group of 12 clinicians located throughout the United States. Of the 174 single implants placed in 129 patients, 151 implants (86.8%) were placed in posterior regions, and 23 were placed in anterior regions; 54.6% of the implants had a length of 10 mm or less. Ninety-two implants were restored with a screw-retained crown, and 82 were restored with a cemented crown (in function 6 months or longer). The survival rate at 6 months was 97.7%. Occlusal screw loosening had an 8.7% occurrence rate (no repeated loosening), and solid conical abutment loosening had a 3.6% occurrence rate (all in one patient). Significant radiographic bone loss was observed on 2.3% of the implants. Data suggest that ITI implants can be a satisfactory choice for posterior single tooth restorations.