Purpose: The purpose of this study was to systematically review the current evidence related to the effects of static loading on the long-term stability of the osseointegrated interface. Materials and Methods: The literature search was conducted using Medline supplemented by SCOPUS and the Cochrane databases as well as hand searching from references of reviewed papers. Relevant studies were selected according to predetermined inclusion and exclusion criteria. Key words used in the search included: dental implant passive fit, dental implant misfit, dental implant static load, dental implant overload, orthodontic forces, and dental implants. Results: The initial database search yielded 192 relevant titles. After the subsequent filtering process, 36 studies were finally selected. Twenty-eight articles involved animal studies and eight articles involved human studies. Conclusions: The results of this systematic review demonstrate that there is no apparent detrimental effect of static loading on osseointegrated dental implants.