Hydraulic calcium silicate–based sealers have been available to dentists for over a decade. How have these materials changed views on root canal treatment? Is there demand for a change in the standard treatment protocols that are accepted when using common sealers? Do hydraulic calcium silicate–based sealers offer a new understanding of the root canal filling material, developing its properties from sealing abilities to healing abilities? A number of issues must be addressed when using hydraulic calcium silicate–based sealers for root canal obturation. This narrative review provides an overview of the clinically relevant aspects of root canal obturation with hydraulic calcium silicate–based sealers. Schlagwörter: cold lateral compaction, intracanal medicament, irrigation, single-cone obturation, warm vertical compaction