Purpose: This study aimed to assess the alteration in keratinized mucosa (KM) dimensions in
the early healing period after implant placement, and the influence of variables obtained during
implant surgery on KM alteration. Materials and Methods: Study participants were consecutively
recruited from patients who had received implants following a non-submerged surgical protocol.
The implant had to be installed in the extraction socket that had healed for more than 6 months
without any soft or hard tissue augmentation. Keratinized mucosa width (KMW), keratinized
mucosa thickness (KMT), soft tissue level (STL), and probing pocket depth (PPD) were
measured at implant placement and 3 and 6 months after implant surgery. The influence of
variables obtained during implant surgery on the 6-month KMW alteration was assessed. Results:
A total of 66 implants in 55 patients who completed the follow-up examination after 6 months
were included in this study. KMW, KMT, and STL significantly decreased at 3- and 6-months
examination by 0.7–1.2 mm. KMW was reduced by 24.6%. Mesial PPD significantly increased
between the 3- and 6-months follow-up. In the multivariate generalized estimating estimations
analysis, the implant diameter negatively influenced the 6-month KMW alteration, but the KMW
at implant surgery positively influenced the 6-month KMW alteration. Conclusions: The KMW
decreased significantly at 3 and 6 months after implant placement. If the initial KMW was wider,
the KMW was reduced more at 6 months after implant placement. Therefore, it is important to
carefully monitor KMW alterations during the early healing period to ensure optimal esthetics
and peri-implant tissue health.
Keywords: mucous membrane, dental implants, wound healing, humans, prospective studies