The dental treatment of patients with epidermolysis bullosa is complex and challenging. In general, a fixed restoration should be aimed for, as this puts only minimal strain on the fragile mucosa. Implants can significantly improve the quality of life of these often young patients. This case report describes the treatment of a 19-year-old female patient with epidermolysis bullosa. All of her impacted teeth were first removed and auxiliary implants were inserted. Bone was then augmented so that eight implants could subsequently be inserted. Finally, the patient received a fixed prosthetic restoration.