A technique that utilizes acid-etched composite resin to maintain antimicrobial-containing acrylic resin strips in situ is described. The advantage of this technique is that placement of a periodontal pack is unnecessary, so control of supragingival plaque is not hindered at the site of the local antimicrobial delivery. The technique described may improve the effectiveness and the clinical acceptability of local antimicrobials in the treatment of periodontal disease