This study assessed the antifungal activity of seven commercial mouthrinses against Candida albicans, the organism often found in denture wearers with denture stomatitis. Screening for efficacy of growth inhibition found that five mouthrinses inhibited the growth of fungi, and their maximum inhibitory dilution values and the fungicidal activity were then determined. Two mouthrinses containing cetylpyridinium chloride were shown to be most effective after determination of the maximum inhibitory dilution and the test of fungicidal activity.