Objective: The aim of this study was to investigate and analyze the angulation of and the various indications for removal of mandibular third molars in Jordanians as a representative Arab sample. Method and materials: The data included in this retrospective study were obtained from the clinical and radiographic records of 1,282 patients undergoing mandibular third molar surgery during a 5-year period from 1994 to 1999. The indications for removal of the mandibular third molars were classified in accordance with age and gender. The angular position of mandibular third molars was registered. Results: A total of 2,252 mandibular third molars were removed from 740 male patients (57.7%) and 542 female patients (42.3%) aged 14 to 67 years. Pericoronitis was the most common indication for surgery, affecting 1,055 teeth (46.8%). Caries was observed in 519 third molars (23.0%). The vertical angular position was most commonly found (1,383 teeth; 61.4%) followed by the mesioangular position (407 teeth; 18.1%). Conclusion: The results obtained in this study are similar to those reported in earlier studies carried out elsewhere, although the incidence of periodontitis among Jordanians was significantly higher and occurred in older patients, and prophylactic removal was performed less frequently than has been reported in other countries.