Purpose: This study investigated the association between satisfaction with the dentition and dental prostheses and personality profiles among patients who received implant-supported prostheses. Materials and Methods: Patients seeking dental implant therapy were recruited for this study. A Dental Impact on Daily Living questionnaire was used to assess dental satisfaction and the effects of implant-supported prostheses on daily living. The NEO Five Factor Inventory (NEO-FFI) was used to assess participants' personality profiles. Participants completed the questionnaires before implant insertion and 3 months after rehabilitation with implant-supported prostheses. Results: Eighty patients (42 men and 38 women, mean age 40.99 years) participated. Patients were more satisfied with their dentition after implant treatment. Neuroticism and conscientiousness had significant relationships with patient satisfaction and impact on daily living both before and after implant therapy. Openness and agreeableness had significant relationships with patient satisfaction and impact on daily living only after implant treatment. Extraversion had a significant relationship with patient satisfaction and impact on daily living only before treatment. After implant treatment, neuroticism was helpful in predicting total satisfaction, as well as satisfaction with appearance, pain, oral comfort, performance, and eating. Conscientiousness was helpful in predicting satisfaction with appearance, whereas openness was helpful in predicting satisfaction with pain. Before implant treatment, neuroticism was helpful in predicting total satisfaction as well as satisfaction with appearance, oral comfort, and performance. Conclusion: Implant-supported prostheses had positive impacts on participants' daily living and satisfaction with the dentition. Personality traits (such as neuroticism, openness, agreeableness, and consciousness) affect patients' daily living and satisfaction with implant-supported prostheses. Selected personality traits might predict patients' satisfaction with implant-supported prostheses prior to treatment. Keywords: dental impacts on daily living, implant-supported prostheses, NEO Five Factor Inventory, patient satisfaction, personality profiles