In this study, 19 patients were treated with 36 Brånemark System MK III TiUnite implants in the maxilla. Definitive implant-supported single crowns were delivered to patients 6 weeks after implant placement. Clinical and radiographic parameters were recorded at baseline, and at 1, 2, and 3 years. Both implant and prosthesis success rates were 94% after 3 years. The average marginal bone loss was 0.97 mm after 3 years. The results of this study indicate that 6-week early loading of TiUnite surface implants in the maxilla was reliable and predictable for this patient population and may offer an alternative to the standard loading protocol.