This study aimed to evaluate the performance of visual and spectrophotometric tooth shade analysis. Two operators independently selected the best match of 3,758 anterior teeth of 106 patients at 3 different dates, using the Chromascop-Complete shade guide. Additionally, tooth color was analyzed 3 consecutive times using a reflectance spectrophotometer. Spectrophotometry showed high agreement values (89.6%); both examiners agreed in 49.7% of the measurements. Visual assessment resulted in significantly darker ratings than spectrophotometry (P .0005). However, a positive association was observed for both procedures (P = .548). Spectrophotometric shade determination seems to be significantly more reproducible than the visual procedure.