Purpose: To evaluate the fracture resistance of computer-aided design/computer-assisted manufactured (CAD/CAM) glass-ceramic incisor crowns fabricated on reverse-tapered preparations. Materials and Methods: Resin abutments with known total occlusal convergence angles (-8, 0, and 12 degrees; n = 20) were scanned with the TRIOS scanner, and glass-ceramic crowns were fabricated with KaVo Arctica, stored in water for either 1 or 30 days, and submitted to fracture test. Results: The fracture resistance of crowns made on reverse-tapered preparations was not significantly different (P = .471) from crowns fabricated over abutments with 0- or 12-degree tapers, irrespective of the water storage period. Conclusion: The fracture resistance of anterior glass-ceramic crowns fabricated over reverse-tapered preparations was similar to that of crowns made on abutments with 0- or 12-degree tapers.