This study evaluated the effects of using a titanium mesh for localized alveolar ridge augmentation. Seven consecutively treated human subjects participated in the study. Clinical, radiographic, laboratory, and histologic/histomorphometric analysis revealed the efficacy of using the titanium mesh in conjunction with intraorally harvested autogenous bone graft and inorganic bovine bone mineral (Bio-Oss). Radiographic measurements detected that a 2.86-mm vertical and 3.71-mm buccolabial ridge augmentation was achieved, while histomorphometry demonstrated that 36.4% of the grafted area consisted of bone. Laboratory measurements revealed 15.08% resorption of the graft for the first 6 months, which appeared to consolidate after placement of the implants. Exposure of the mesh did not appear to compromise the result.