SupplementDOI: 10.11607/prd.3123, PubMed ID (PMID): 29513776Pages 97-103, Language: EnglishCrespi, Roberto / Capparé, Paolo / Crespi, Giovanni / Gastaldi, Giorgio / Romanos, Georgios E. / Gherlone, EnricoThe aim of this study was to compare midfacial soft tissue assessment and horizontal width changes of fresh socket implants in immediate and delayed prosthetic restorations. Patients requiring extractions in the maxillary esthetic zone were recruited. In one group, 30 implants were placed using an immediate loading approach; in the second group, 30 implants were loaded after a period of 3 months. At the 4-year follow-up, statistically significant differences (P .001) were found. Immediate implants restored on the day of surgery demonstrated more stable midfacial soft tissue levels and bone volume maintenance than delayed implants.