The harm that tobacco use does to health is irrefutable. The evidence of careful scientific articles testifies that its use, smoke or smokeless and inhaling side stream smoke from cigarettes increases risk of many serious diseases particularly ORAL CANCER. However tobacco use is one of the major preventable causes of disease and premature death. In an ironic twist to the relationship between tobacco and human health, it would seem that the future of the tobacco plant may lie in growing vaccines against cancer. It is observed that the vaccine derived from tobacco plant can be used for treatment of various cancers like lymphoma, epidemic infections like norovirus infection, and as therapy against tobacco addiction. The same plant which is responsible for causing cancer may offer a way to treat the disease. However, government still hesitate to act progressively to reduce tobacco use as it may affect the economic benefits that a country derives from growing, processing, manufacturing, exporting and taxing tobacco. This poster aims at gaining the benefits from the disastrous tobacco, by highlighting the use of tobacco plant in developing viable vaccine . Keeping in mind the economy of country, tobacco plant cultivation can be used for derivation of useful tobacco vaccine rather than harmful tobacco smoke. Keywords: tobacco, nicotine, cancer, vaccine