Pages 139-142, Language: EnglishSandhu, Sumeet / Kaur, TejinderInvasive aspergillosis in healthy hosts is a very rare occurrence, but it may become pathogenic under certain circumstances. In the head and neck region, aspergillosis usually involves the maxillary sinus. This case report describes secondary Aspergillus infection of the mandible in a 35-year-old female patient in whom the maxillary sinus was primarily involved 5 years previously.