The aim of this article is to explain the use of a computer-aided three-dimensional planning protocol in combination with previously placed mini-implants and computer-aided design/computer-assisted manufacture (CAD/CAM) technology to restore a completely edentulous patient. Mini-implants were used to establish a setup for computerized tomographic imaging and a surgical template. The software and its three-dimensional simulation allowed the authors to plan ideal implant placement, digitally integrating the future prosthetic and anatomic situations to design the definitive superstructure. The CAD/CAM superstructure is produced digitally with a precise fit and occlusion and good esthetics, and is placed immediately after surgery Keywords: computer-aided design/computer-assisted manufacture, dental implants, guided surgery, immediate loading, mini-implants