Purpose: To investigate the impact of software version on the accuracy of an intraoral scanning device. Materials and Methods: A master tooth was scanned with a highprecision optical scanner and then 10 times with a CEREC Omnicam scanner with software versions 4.4.0 and 4.4.4. Discrepancies were measured using quality control software. Results: Mean deviation for 4.4.0 was 36.2 ± 35 μm and for 4.4.4 was 20.7 ± 14.2 μm (P ≤ .001). Conclusion: Software version has a significant impact on the accuracy of an intraoral scanner. It is important that researchers also publish the software version of scanners when publishing their findings.