The success of endosseous dental implants is enhanced when sufficient bone is present to stabilize the implant. If adequate bone for full coverage of the implant is not possible, then the use of guided bone regeneration to regenerate the missing bone has been shown to be a predictable solution. Defect size can often limit the amount of soft tissue available for coverage of the membrane, which is essential in obtaining an optimal result when using regenerative and osseointegrative principles. The treatment philosophy demonstrated in this case report uses controlled subperiosteal tissue expansion to facilitate the incorporation of guided bone regeneration with the subsequent placement of endosseous dental implants. This treatment modality provided a successful treatment for an otherwise compromised case.