There is a constant evolution of newer file systems with different motion kinematics to refine the field of endodontics. This has not only revolutionised the way clinicians shape the root canal system, but also confuses the clinician as to which system to choose. Hence, this poster aims at comparing different contemporary motion kinematics like rotary, reciprocation motion, and the vertical vibration of a self-adjusting file, their efficiency on various clinically-relevant parameters like fatigue life, post-operative pain, and shaping ability and provide a practical guide in choosing the appropriate system that best suits the clinical situation. Keywords: rotary, reciprocation, self-adjusting file, post operative pain, shaping ability, cyclic fatigue