Aim: The objective of this case study is to present the manufacturing process and delivery of a removable partial denture (RPD) using computer-aided design/computer-aided manufacturing (CAD/CAM) technology. Materials and methods: A 46-year-old female patient presented at the Federal University of Rio Grande do Norte complaining of the lack of retention in her mandibular RPD. After the design and preparation of the abutment teeth, further appointments were made. In the first appointment, intraoral scanning (IOS) with a Trios scanner was performed, followed by virtual planning of the framework. The RPD was then printed, invested, cast by induction, and polished. In the second appointment, the RPD was delivered. Conclusion: The technique proved to be efficient in terms of clinical time and sufficient for patient comfort and satisfaction. Keywords: 3D printing, removable partial denture, precision, CAD/CAM, accuracy, trueness