International Journal of Periodontics & Restorative Dentistry, Pre-Print
DOI: 10.11607/prd.7488, PubMed ID (PMID): 3980853214. gen 2025,Pagine 1-25, Lingua: IngleseRoncati, Marisa / Nava, Paolo / Sabri, Hamoun / Parma-Benfenati, Lucrezia / Kumar, Purnima S.This study aimed to assess the effectiveness of repeated subgingival instrumentation combined with 980 nm diode laser decontamination in the non-surgical treatment of deep periodontal pockets. A total of 40 otherwise healthy patients with generalized periodontitis, encompassing 1,168 sites with deep pockets, were included and baseline PPD, bleeding on probing (BOP), gingival recession (REC), clinical attachment level (CAL), and plaque index (PI) were recorded. Each patient underwent non-surgical laser-assisted periodontal therapy and was enrolled in a maintenance program with three-month recall visits during the first year of follow-up. In non-responding sites, site-specific non-surgical instrumentation was repeated during follow-up visits. The achievement of pocket closure (PPD ≤ 4 mm with negative BOP) was evaluated as the primary outcome. Changes in the above parameters were also measured at 3 months (T1) and 1 year (T2). Additionally, a logistic regression model was constructed to explore the association of pocket closure at T2 with several predictor variables. At the three-month evaluation, 677 of the treated sites (57.96%) achieved pocket closure. This number increased significantly after one year, with 977 out of 1,168 sites (83.65%) requiring no further treatment. The logistic regression analysis indicated that a higher number of roots, older age, history of diabetes mellitus, and greater baseline PPD were associated with lower pocket closure at T2. Within its limitations, the present study demonstrates that the outcomes of initial non-surgical periodontal therapy can be further enhanced by repeated site-specific laser assisted non-surgical instrumentation, scheduled quarterly during the first year of follow-up.
Parole chiave: Non-surgical therapy, revaluation, periodontal treatment, diode laser, curettes, full mouth approach
International Journal of Periodontics & Restorative Dentistry, 3/2023
DOI: 10.11607/prd.6490, PubMed ID (PMID): 37141081Pagine 329-335, Lingua: IngleseParma-Benfenati, Stefano / Mastrangelo, Filiberto / Cardo, Federica / Roncati, Marisa / Parma-Benfenati, Lucrezia / Aimetti, Mario / Nevins, MyronA 12-month prospective consecutive case series study was conducted to evaluate the effectiveness of a novel porcine collagen matrix to correct moderate to severe buccogingival recession defects. A total of 10 healthy patients (8 women and 2 men; age range: 30 to 68 years) with 26 maxillary and mandibular recession gingival defects > 4 mm deep were included. Healthy maturation of gingival tissues with natural color and texture matching the adjacent soft tissue areas were observed at all reevaluation visits. Complete root coverage was not achieved in all cases, possibly due to severe buccal bone loss in most of the selected cases, which negatively impacted the results. Nevertheless, when a novel porcine collagen matrix was used, a mean root coverage of 63.15% was achieved, and gains in clinical attachment level and keratinized tissue height were seen. Future randomized clinical trials are needed to further explore the potential of porcine collagen matrix for treatment of localized gingival recession defects.
International Journal of Periodontics & Restorative Dentistry, 6/2021
DOI: 10.11607/prd.5009Pagine 819-825, Lingua: IngleseRoncati, MarisaThis case report emphasizes how home and professional care can impact clinical outcomes following nonsurgical mechanical therapy with the adjunctive use of a diode laser to treat failing implants. Localized severe peri-implant disease was diagnosed in a patient who was susceptible to periodontal disease, not compliant, and did not accept the surgical approach. A cause-related, diode laser-assisted, nonsurgical treatment was therefore implemented, according to a dedicated protocol, in four closely scheduled appointments. The patient's oral hygiene skills became extremely effective. She then adhered to a bimonthly maintenance protocol in the first follow-up year and quarterly in the subsequent year. Bone remineralization was detected on comparative periapical radiographs 2 years after the diagnosis of peri-implantitis. At the 2-year observation, the patient's high standard of home care and dedicated maintenance arrested the progression of peri-implantitis and yielded clinical and radiographic improvements following nonsurgical mechanical therapy with adjunctive repeated application of a diode laser.
International Journal of Periodontics & Restorative Dentistry, 4/2021
Pagine 511-519, Lingua: IngleseParma-Benfenati, Stefano / Tinti, Carlo / Roncati, MarisaThe aim of this classification is to diagnose and grade four different types of soft tissue deficiency around loaded, osseointegrated implants according to increasing severity. The suggested soft tissue augmentation to increase the width of the peri-implant keratinized mucosa will improve the long-term stability of peri-implant tissues.
International Journal of Periodontics & Restorative Dentistry, 1/2021
Pagine 23-30, Lingua: IngleseMaino, Giuliano B. / Parma-Benfenati, Stefano / Maino, Giovanna / Maino, Giovanni N. E. / Benfenati, Lucrezia Parma / Roncati, MarisaMAPA-cision, named after those who first introduced the method, is a novel simplified regenerative technique for periodontal-orthodontic cases that can be used in all circumstances where bone thickening is required. It is an innovative, minimally invasive piezoelectric surgical procedure designed to facilitate orthodontic tooth movement while simultaneously increasing bone thickness with guided bone regeneration principles. A new regenerative device consisting of a resorbable collagen membrane with filling materials (a “bone bundle” or “small sausage”) is inserted through a tunneling procedure to increase the bone envelope width by allowing the teeth to move within an enhanced periodontal support.
International Journal of Periodontics & Restorative Dentistry, 4/2020
DOI: 10.11607/prd.4647, PubMed ID (PMID): 32559030Pagine 487-496b, Lingua: IngleseParma-Benfenati, Stefano / Tinti, Carlo / Romano, Federica / Roncati, Marisa / Aimetti, MarioThe aim of this retrospective study was to evaluate long-term clinical and radiologic outcomes of submerged and nonsubmerged guided bone regenerative treatments for peri-implantitis lesions. Strict methods of implant-surface decontamination and detoxification were performed. Data on clinical probing depth, soft tissue measures, and marginal bone level that were documented by comparative radiographs were obtained from 45 patients, for a total of 57 implants prior to treatment and at the latest follow-up. The average followup period was 6.9 years (range: 2 to 21 years). Analysis of implant-based data revealed a success rate of 70.2% for a total of 40 implants. Recurrence of periimplantitis was observed on 9 implants, and 8 implants were removed. The regenerative procedures, under a strict periodontal control, were effective in the treatment of moderate to advanced peri-implantitis lesions.
International Journal of Periodontics & Restorative Dentistry, 5/2017
DOI: 10.11607/prd.2934, PubMed ID (PMID): 28817127Pagine 646-654, Lingua: IngleseRoncati, Marisa / Gariffo, Annalisa / Barbieri, Cinzia / Vescovi, PaoloThe clinical effects of treatment with 808- and 980-nm diode lasers as an adjunct to a uniform and consistent nonsurgical periodontal treatment protocol (NSPTP) for initial probing pockets ≥ 6 mm with a 10-year follow-up were evaluated. In total, 24 patients (16 test cases and 8 control cases) were treated with the NSPTP. The control group (CG) was treated only with nonsurgical conventional therapy, while the test group (TG) received treatment with thermal diode lasers (wavelength of 808 or 980 nm). All patients had recall visits every 3 months and were reevaluated at 1 year after NSPTP. Following the 1-year follow-up, patients were monitored at 4-month intervals for the remaining 9 years. In total, 646 teeth (433 in TG [124 multirooted teeth and 309 single-rooted teeth] and 213 in CG [64 multirooted teeth and 149 single-rooted teeth]) were included. The initial probing pocket depth (PPD) in single-rooted teeth from TG patients decreased from an average of 6.7 mm to 3.3 mm after 1 year, and to 2.3 mm after 10 years. The mean increase in clinical attachment level (CAL) was 3.8 mm. The initial PPD of single-rooted teeth in CG patients decreased from an average of 6.4 mm at baseline to 4 mm after 1 year and 3.3 mm after 10 years. The mean increase in CAL was 2.5 mm in CG. In the TG, the PPDs of multirooted teeth decreased from 6.2 mm to 3.3 mm after 1 year, where they remained stable for 10 years. The mean increase in CAL was 2.2 mm in this group. In the CG, the PPDs for multirooted teeth decreased from 7 mm to 5.8 mm after 1 year and were 5.1 mm after 10 years. The mean increase in CAL was 1.9 mm. The TG had significantly better clinical parameters than the CG, including reduced tooth loss. Compared to conventional debridement alone, the use of thermal diode lasers with NSPTP improves PPD and increases CAL in periodontal pockets ≥ 6 mm over the long term.
International Journal of Periodontics & Restorative Dentistry, 2/2016
DOI: 10.11607/prd.2600, PubMed ID (PMID): 26901297Pagine 188-197, Lingua: IngleseRoncati, Marisa / Gariffo, AnnalisaA total of 25 patients were treated with a nonsurgical periodontal treatment protocol (NSPTP) consisting of four appointments (three within 1 week and one approximately 30 days later). Nonsurgical periodontal instrumentation was implemented, with the adjunctive use of thermal diode lasers (wavelength of 808 or 980 nm). The patients were scheduled for recall visits every 3 months and reevaluated 1 year post-NSPTP. They were subsequently monitored at 4-month intervals for the remaining 2-year follow-up maintenance period. In total, 698 teeth (210 multirooted and 488 single-rooted) were included in the study. The mean bleeding on probing was 43% at baseline and decreased to 12% at 12 months and to 8% at 3 years. The initial ≥ 6-mm probing pocket depth (PPD) in single-rooted teeth decreased from 6.2 mm at baseline to a mean of 1.8 mm at 12 months and remained at 1.8 mm at 3 years, with a mean clinical attachment level (CAL) gain of 4.4 mm. In multirooted teeth, the PPD decreased from 6.7 mm to a mean of 3.9 mm at 12 months and 3.6 mm at 3 years, with a mean CAL gain of 2.9 mm. The mean overall recession was 0.3 mm at baseline, 0.1 mm at 1 year, and 0.3 mm at the 3-year follow-up. In the short-term followup period, uniform and consistent implementation of the NSPTP used here with adjunctive use of thermal diode lasers seemed to convey therapeutic benefits, stable periodontal soft tissue levels, and satisfactory esthetics in patients with moderate to severe chronic periodontitis. The present protocol is relevant as a treatment option for medically compromised patients, those who refuse or delay surgical treatment, or those who present with other limitations.
International Journal of Periodontics & Restorative Dentistry, 5/2015
DOI: 10.11607/prd.2374, PubMed ID (PMID): 26357692Pagine 624-636, Lingua: IngleseParma-Benfenati, Stefano / Roncati, Marisa / Galletti, Primo / Tinti, CarloThis case series presents clinical outcomes on reentry using regenerative submerged and nonsubmerged approaches in peri-implant defects; pre- and posttreatment assessments of nine implants in six patients are presented. A mean bone fill value of 91.3% with a 4.88-mm mean bone gain was obtained. Neither approach led to additional bone loss or required additional bone augmentation procedures. Strict methods of implant surface decontamination and detoxification were used on all patients, regardless of implant surface characteristics. The regenerative procedure was effective in the treatment of moderate to advanced peri-implantitis lesions without compromising the previous fixed implant-supported prostheses. These preliminary results are reasonably encouraging in that all cases showed bone gains. Nevertheless, caution must be exercised when determining reosseointegration, because it is not possible to ascertain it in clinical practice.
International Journal of Periodontics & Restorative Dentistry, 6/2014
DOI: 10.11607/prd.2128, PubMed ID (PMID): 25411729Pagine 748-755, Lingua: IngleseParma-Benfenati, Stefano / Roncati, Marisa / Galletti, Primo / Tinti, CarloThis case series presents the use of a resorbable "dome device" made of a slow, long-lasting resorbable suturing material to support the barrier creating and maintaining a secluded space to promote bone regeneration. Acellular dermal matrix or cross-linked resorbable collagen membrane, as barriers, combined with mineralized freeze-dried bone allograft, with simultaneous implant placement, were utilized in reconstructing non-space-making defects. Eight implants in six healthy patients were treated with a combination of these resorbable regenerative materials. Only one of seven was treated with a nonsubmerged approach. All sites remained completely covered and no implant exposure occurred during healing. At the 9- to 24-month reentry surgeries, the clinical bone density was equivalent to that of the native bone and the mean number of final exposed threads was 0.5. The mean buccal bone thickness achieved was 3.12 mm, with a mean total coverage of exposed threads in approximately 87.5% of the cases.
