Clear aligners are, without doubt, the most popular option in current clinical orthodontic practice. As knowledge relating to the latter has increased, different treatment modalities have been proposed. The digital workflow plays a significant role in the treatment of malocclusion, giving a precise indication of how much and at what point each tooth will move; thus, it can be considered to provide the most individualised prescription possible. Many brands offer clear aligners, and the decision of which one to use depends entirely on the clinician; nevertheless, the option to fabricate them in one’s own clinic is a cost-effective and predictable process of which all clinicians should be aware.