Mandibular deviation (MD) is a common reconstruction sequela after segmental
mandibulectomy. Although proper postoperative rehabilitation is critical for MD management
and minimization, the information available is limited. This report describes postoperative
rehabilitation with an occlusal splint fabricated using computer-aided design (CAD) and
computer-aided manufacturing (CAM) (CAD/CAM-OS) and the results of a threedimensional
occlusal analysis using an intraoral scanner after hemimandibulectomy and plate
reconstruction. Despite the short follow-up, adherence to postoperative rehabilitation with
CAD/CAM-OS for MD correction, even during radiotherapy, was demonstrated by the digital
workflow and analysis results.