This study examined changes in facial geometry while playing wind instruments. Nine musicians participated (6 men, 3 women, mean age 52 years) in part 1 of the study, and 3 musicians participated (3 women, mean age 41 years) in part 2. In part 1, the high and low notes of each instrument were selected as test sounds. Facial geometry data were recorded using a 3D scanner. In part 2, facial geometry data were recorded using a 4D scanner while a melody was played. Data were superimposed and analyzed using 3D analysis software. Numerical values and color maps of deviations were obtained. The results of part 1 revealed that the median 3D deviation was 1.1 mm (range 0.42-1.45 mm), indicating that facial geometry while playing high and low notes was varied. The results of part 2 showed that the stable part was the frontal region and dorsal part of the nose. The approach used in this study has potential applications for evaluating facial geometry during musical instrument performances.