Purpose: To evaluate the morphological properties, phase transformation, and microshear bond strength of composite cement to bioglass-coated zirconia surfaces treated with Nd:YAG laser. Materials and Methods: Seventy-five zirconia disks were divided into five groups (n = 15). Group C received no surface treatment (control). Group S was subjected to sandblasting with 50-μm aluminum oxide particles. Group B samples were coated with bioglass 45S5. Groups BL9 and BL5 received bioglass coating and laser irradiation with 9 J/cm2 and 5 J/cm2 energy density. Morphological assessment was done using atomic force microscopy (AFM) and scanning electron microscopy (SEM). Zirconia phase transformation was assessed by XRD. Microhear bond strength testing was performed using a modified microtensile tester. The data were analyzed using the Welch test and the Games-Howell test (p 0.05). Results: The sandblasted and bioglass-coated groups showed the highest bond strengths compared to other groups (p 0.05). Group S showed the highest surface roughness and the highest frequency of cohesive failure. In all samples, the tetragonal phase decreased after surface treatment. Groups BL9 and BL5 showed some levels of tetragonal to cubic phase transformation. Conclusion: Bioglass coating of zirconia surfaces (using the slurry method) can increase its microshear bond strength comparable to that of sandblasting. Surface roughness of sandblasted zirconia was the highest among all methods. Irradiation of Nd:YAG laser on bioglass-coated zirconia surfaces is not effective and decreases its bond strength compared to sandblasting and bioglass coating. Increasing the Nd:YAG laser energy density cannot increase the surface roughness of bioglass-coated zirconia surfaces. Bioglass coating results in transformation of the tetragonal to the cubic phase. Keywords: Nd:YAG laser, bioglass, zirconia surface, bond strength, phase transformation