Purpose: To evaluate the effect of axial wall height (AWH) on failure resistance of CAD-CAM adhesively-bonded, all-ceramic crowns on molar preparations with a conservative total occlusal convergence (TOC). Materials and Methods: 60 newly extracted maxillary third molars were divided into 5 groups (n = 12) and prepared for all-ceramic crowns with occlusal cervical AWH of 0, 1, 2, 3, and 4 mm, all containing a conservative 10-degree TOC. Scanned preparations were fitted with lithium-disilicate glass-ceramic crowns using a self-adhesive resin-composite luting agent after intaglio surface preparation with hydrofluoric acid and silane. Specimens were stored at 37°C/98% humidity for 24 h and tested to failure at a 45-degree angle applied to the palatal cusp on a universal testing machine. Mean results were analyzed using ANOVA and Tukey's test (p = 0.05). Results: Preparations containing 2, 3, and 4 mm AWH demonstrated similar and higher failure resistance than the 0- and 1-mm axial wall height groups. Conclusions: Under the conditions of this study, evidence is presented that under certain conditions CAD-CAM adhesive technology may compensate for less than optimal AWH. Based on both failure load results and failure mode analysis, adhesively-luted maxillary molar CAD-CAM crowns based on a preparation containing 10-degree TOC require at least 2 mm AWH for adequate resistance and retention. However, adoption of these findings is cautioned until both fatigue analysis and appropriate clinical evidence has been provided. Keywords: CAD-CAM, adhesion, lithium disilicate, failure load, axial wall height, total occlusal convergence