Dental abnormalities associated with ectodermal dysplasia (ED) can result in severe functional and esthetic problems. To correct these problems, dental implants have increasingly become the treatment of choice. This patient study illustrates the use of implants to rehabilitate a 20-year-old ED patient who initially presented with only 2 permanent and 6 primary teeth in the maxilla. Along with conventional endosseous implants, 2 specially designed zygomatic implants were utilized to avoid the need for bone grafting in the patient's severely resorbed maxilla. This expedited achievement of the final satisfactory result. Keywords: ectodermal dysplasia, endosseous dental implants, implant-supported dental prosthesis, zygoma