Purpose: To determine and compare the accuracy of an advanced surgical template based on computer-aided design/computer-assisted manufacture (CAD/CAM) with the conventional surgical template in different respects such as entry point, length, and osteotomy angle. Materials and Methods: Computed tomography (CT) scanning of a dentate epoxy mandible was performed and its three-dimensional computerized model was simulated. Sixteen rapid-prototyped models were fabricated and divided into two groups. In the first group, a radiographic template was fabricated and placed on the model during CT scanning and then was modified to the conventional surgical template form. In the second group, a coordinate measuring machine was used to reformat a nonanatomic radiographic template fabricated by a stereolithographic machine, and four implants were planned and then placed in the jaw. The differences between planned and actual mesiodistal and buccolingual entry points, lengths, and angles of the implants were measured. Statistical analysis was performed with the Mann-Whitney and Friedman tests to detect differences between groups. Results: The average differences between the planned and actual entry points in the mesiodistal and buccolingual directions, lengths, and angles of the implants and the osteotomy showed a considerable reduction in the CAD/CAM group versus the conventional group (P .005). Conclusion: The accuracy of implant placement was improved using an innovative CAD/CAM surgical template. Keywords: computed tomography, computer-aided design, coordinate measuring machine, dental implants, stereolithography, surgical templates