This study evaluated the efficacy of a new occlusal analysis sytem (Dental Prescale System) composed o pressure-sensitive sheets and a computer for analysis for complete denture wearers. In the laboratory portion of the study, the system registered values that were greater than the actual applied loads (mean 6.3 ± 10.6 N). Clinical measurements of five parameters related to the analysis of occlusion were made using two groups: 50 wearers of nonadjusted complete dentures and 50 wearers of adjusted prostheses. An error discrimination rate of 16% resulted between the two groups. This system is capable of measuring occlusal pressure at every contact point and can be considered a useful method for occlusal analysis and patient screening.