This preliminary study investigated the influence of different oral prosthodontic interventions on quality of life related to voice and oral health in elderly people and the relation between these conditions. Forty-five elderly people who had completed prosthodontic rehabilitation treatments were divided into three groups according to dental conditions and answered two protocols: voice-related quality of life and oral health impact profile. Despite the small sample size, the elderly people in this study presented no differences between the groups and showed a relationship between oral and vocal health aspects.