Purpose: A total of 24 zirconia-based single tooth-retained restorations inserted in 18 patients were followed up for 15 to 61 months (mean: 35 months). Materials and Methods: Recall consisted of dental and hygiene status as well as quality assessment and check for occlusal relationship. One patient was lost to follow-up. In the incuded patients, 15 central incisors, 3 canines, and 5 lateral incisors replaced 16 lateral incisors and 7 central incisors, mostly in the maxilla (n = 17). Results: One retainer debonded, two pontics experienced incisal chip-offs, and one patient showed an orthodontic relapse. The success rate was estimated at 82.4%, with 100% survival at 36 months. Conclusion: Technical protocol and occlusal protection are crucial.