This article describes the digital fabrication of a surgical obturator (SO) using only computed tomography (CT) data from the tumor area. This procedure is a departure from the traditional method of making an impression and obtaining a patient cast prior to surgery to allow for SO fabrication. The present approach allows for a virtual resection based on the patient's CT image; the SO is digitally designed with animation software and fabricated by 3D printing. The SO is relined with a denture reliner at the time of surgery to complete the obturation of the maxillectomy defect.