Purpose: To assess the accuracy of three cone beam computed tomography (CBCT) systems in misfit detection at the implant-abutment joint. Materials and Methods: A total of 32 implants were placed in dry human mandibles. Porcelain-fused-to-metal crowns, both with and without a 200-μm-thick gap at the implant-abutment joint, were placed and then scanned using three CBCT systems: Picasso Trio (PT), OP300 (OP), and Scanora 3D (SC). Images were assessed, and area under the receiver operating characteristic curve (Az) values were compared (a = .05). Results: Az values obtained with PT (0.86) were significantly higher than with OP (0.63) and SC (0.64) (P .05). Conclusion: Images acquired with PT allowed for more accurate misfit detection at the implant-abutment joint due to higher contrast resolution.