Purpose: To assess the prevalence of depression and somatization in patients with temporomandibular disorders (TMD) in a Brazilian population-based cross-sectional survey. Materials and Methods: A total of 1,643 subjects were assessed for TMD using the Research Diagnostic Criteria for Temporomandibular Disorders Axes I and II and were assessed for depression and somatization using the Graded Chronic Pain Scale. The data were cross-tabulated for comparison between TMD subjects and controls. Results: TMD subjects had significantly worse depression and somatization levels than controls in the RDC/TMD Axis II. The levels were also worse in most Axis I TMD groups (muscle disorders and arthralgia/osteoarthritis/ osteoarthrosis). Conclusion: TMD subjects had worse depression and somatization, particularly in diagnostic groups with higher pain/disability levels.