PubMed ID (PMID): 28653050Pages 186-202, Language: EnglishHein, Sascha / Tapia, Javier / Bazos, PanaghiotisContemporary dental patients present with high expectations and demand seamless optical integration of restorative interventions. As a result, clinicians and technicians are required to develop methodologies that remain practical yet increase the accuracy and objectivity of shade analysis and estimation. There have been significant advances in digital technologies over the past 20 years, with digital photography being at the forefront. Digital photography has made an immediate and profound impact on applied clinical dentistry, primarily due to instantaneous image visualization and distribution. However, standardization protocols in terms of image acquisition and objective analysis remain equivocal. By utilizing reflective cross-polarized light digital photography with a standardized white balance gray reference card serving as the known reference, in conjunction with a specific digital single-lens reflex (DSLR) camera profile and digital photographic processing software working in the CIE L*a*b* (1976) color space, one can achieve standardized image acquisition and subsequent objective image analysis. The goal of this systematic approach is to identify the most efficient and effective means to generate consistent and optimum visual integration and restorative outcomes through numerical quantification, in order to enable clinicians and technicians to work predictably even when they are in different geographic locations.