DOI: 10.11607/prd.3397, PubMed ID (PMID): 29444198Pages 389-394, Language: EnglishFiorellini, Joseph P. / Norton, Michael R. / Luan, Kevin WanXin / Kim, David Minjoon / Wada, Keisuke / Sarmiento, Hector L.The objective of this study was to evaluate the effectiveness of precise threedimensional hydroxyapatite printed micro- and macrochannel devices for alveolar ridge augmentation in a canine model. All grafts induced minimal inflammatory and fibrotic reactions. Examination of undecalcified sections revealed that both types of grafts demonstrated bone ingrowth. The majority of the bone growth into the block graft was into the channels, though a portion grew directly into the construct in the form of small bony spicules. In conclusion, bone ingrowth was readily demonstrated in the middle of the implanted printed devices.