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  • Quintessence Publishing Deutschland
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Robert E. Marx

Bisphosphonat-induzierte Osteonekrose der Kiefer

Ätiologie, Prävention, Behandlung

1. Auflage 2013
Book
Softcover, 184 pages, 261 illus
Language: German
Categories: Oral/Maxillofacial Surgery, Oral Surgery, Student literature

Stock No.: 18960
ISBN 978-3-86867-107-0
QP Deutschland

88,00 € 28,00 €
28,00 € 8,00 €
1
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Der Zusammenhang zwischen bestimmten Formen der Bisphosphonattherapie und Knochennekrosen der Kiefer ist seit mehreren Jahren bekannt. Robert E. Marx erläutert in diesem Buch die kausalen biologischen Mechanismen des Phänomens und stellt Behandlungsprotokolle für alle Stadien der Bisphosphonat-induzierten Osteonekrose vor.

Das Buch bietet darüber hinaus eine vereinfachte Einteilung dieser Stadien, Erläuterungen zu einem Serum-CTX-Test für die orale Bisphosphonattherapie, neueste Erkenntnisse zu den häufig mit Bisphosphonaten behandelten Krankheiten Osteopenie und Osteoporose sowie eine Methode zur Risikoabschätzung hinsichtlich der Entwicklung einer Osteonekrose unter Bisphosphonatmedikation. Ausführliche Falldarstellungen liefern praktische Anleitungen zu allen behandelten Problemen und Aspekten. Im Anhang dieser Ausgabe folgt im Anschluss an ein Nachwort des Übersetzers PD Dr. med. Dr. med. dent. Christian Walter der vollständige Text der S3-Leitlinie.

Inhalt
Kapitel 1. Beschreibung und Geschichte der Bisphosphonat-induzierten Osteonekrose der Kiefer
Kapitel 2. Wirkweise und Pharmakokinetik der Bisphosphonate
Kapitel 3. Medizinische Indikationen der Bisphosphonate
Kapitel 4. Osteopetrose: ein genetisches Analogon zur Bisphosphonat-induzierten Osteonekrose der Kiefer
Kapitel 5. Risiko, Prävention und Management der durch intravenöse Bisphosphonate induzierten Osteonekrose
Kapitel 6. Risiko, Prävention und Management der durch orale Bisphosphonate induzierten Osteonekrose
Kapitel 7. Klinisch pathologische Fallsammlung
• Nachwort von Christian Walter
• S3-Leitlinie "Bisphosphonat-assoziierte Kiefernekrose (BP-ONJ) und andere Medikamenten-assoziierte Kiefernekrosen"

alt
Author

Robert E. Marx DDS, FACS

United States of America

Well known as an educator, researcher, and innovative surgeon, Dr Marx is professor of surgery and chief of the Division of Oral and Maxillofacial Surgery at the University of Miami Miller School of Medicine. As a researcher, he has made valuable contributions in the use of hyperbaric oxygen following radiation therapy, in the development of platelet-rich plasma, and in elucidating the relationships between smoking and carcinogenesis. He also pioneered the clinical applications of recombinant human bone morphogenetic protein and stem cell use and was the first to identify what is now known worldwide as bisphosphonate-induced osteonecrosis of the jaws. He has also developed new concepts and treatments for pathologies within OMS as well as new techniques in reconstructive surgery.

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