Purpose: The aim of this article was to present the oral rehabilitation of a patient with a large, created intraoral defect after the surgical extirpation of a pathologic process. Materials and Methods: On osseointegrated oral implants, a bar was fabricated to support a partial overdenture by means of attachments. Results: The treatment was successful and the construction has been in service for more than 5 years. Conclusion: In cases with large intraoral defects removable dentures may have clinical advantages over fixed partial dentures. In this patient the restoration of missing teeth, alveolar crest, and soft tissue was accomplished at the same time oral function was restored, and good oral hygiene access was obtained.