Purpose: The present study was carried out to evaluate Cerana Class I and II tunnel preparations in combination with Cerana inlays. Materials and Methods: Sixty- eight patients were treated with 89 Cerana restorations, 53 in the maxilla and 36 in the mandible. Of these, 47 were Class I and 42 were Class II. The restorations were examined after 1, 2, and 3 years by the author together with the treating clinician. For the evaluation, the California Dental Association quality evaluation system was used. Results: At the 3- year recall, 59 (66%) restorations were examined. One restoration had been exchanged after 1 week, and 10 (11%) restorations had fractured before the 3-year follow-up. A total of 19% of the marginal ridges had fractured over the 3 years. These fractures were in connection with Class II tunnel preparations, except for one Class I filling. All of the Cerana inlays had acceptable marginal adaptation. Marginal discoloration was seen around 8% of the restorations. The color match was excellent, and the majority of the restorations had a smooth surface. Caries was seen in five teeth, three in connection with fractured marginal ridges. Conclusion: The results indicate that Cerana is an alternative to composite resin restorations in Class I situations, but should be avoided in connection with Class II tunnel preparations.