Purpose: The precision of a computer-aided design/manufacturing (CAD/CAM) system to manufacture zirconium dioxide copings with a predetermined internal space was investigated. Materials and Methods: Two master models were produced in acrylic resin. One was directly scanned by the Decim Reader. The Decim Producer then manufactured 10 copings from prefabricated zirconium dioxide blocks. Five copings were prepared, aiming for an internal space to the master of 45 µm. The other five copings were prepared for an internal space of 90 µm. The second test model was used to try in the copings produced. The obtained internal space of the ceramic copings was evaluated by separate measurements of the master models and inner surfaces of the copings. The master models were measured at predetermined points with an optical instrument. The zirconium dioxide copings were measured with a contact instrument at the corresponding sites measured in the masters. Results: The first group of copings had a mean internal space to the scanned master of 41 µm and of 53 µm to the try-in master. In general, the internal space along the axial walls of the masters was smaller than that along the occlusal walls. The second group had a mean internal space of 82 µm to the scanned master and of 90 µm to the try-in master. Conclusion: The aimed-for internal space of the copings was achieved by the manufacturer. The CAD/CAM technique tested provided high precision in the manufacture of zirconium dioxide copings.