Purpose: The aim of this study was to investigate the optimal design of a fiberreinforced composite (FRC) framework to obtain the maximum reinforcement for fixed partial dentures (FPDs) under three different loading conditions using threedimensional finite element (FE) analysis. Materials and Methods: A three-unit FPD replacing the maxillary right lateral incisor was constructed using FE analysis software (ANSYS 10.0, ANSYS). A fiber framework of the pontic was designed with three variations: with the main framework curved labially (FRC1), located in the center (FRC2), or curved lingually (FRC3). Each framework was compared with a hybrid composite FPD without any fiber reinforcement (C-FPD). A lateral load was applied to the three different loading points of the pontic 0 mm, 3 mm, and 6 mm from the incisal edge, each representing loading conditions 1, 2, and 3, respectively. Results: Localized high stress concentration was observed around the connectors under all loading conditions. In all FRC-FPD models, the FRC framework showed stress-bearing capacity for the FPD. The highest stress reduction ratio under all loading conditions was obtained using the FRC1 model. The FRC1 framework also best reduced displacement of the framework. Conclusion: This study suggests that the optimum design of an FRC framework is to labially curve the FRC of the main framework at the region of the pontic.