The purpose of this study was to compare the strain of complete dentures with and without full palatal coverage and to determine the effect of reinforcement. Three types of maxillary complete dentures (with palate, without palate, and without palate but with reinforcement) were fabricated, and reinforcements were made from a cobaltchromium alloy. Strain gauges were attached to the polished surface, and a vertical load was applied in the region of the first premolar and first molar. The strains were statistically compared. The greatest strain occurred on the anterior palatal surface and was tensile in the denture with palatal coverage and compressive in the denture without palatal coverage. Significantly less strain occurred in dentures with reinforcement than without reinforcement.