Purpose: To compare different dental bonding systems that are currently available on the market. Materials and Methods: A total of 100 extracted, intact third molars were coated in resin, cut, and divided into 10 groups of 10 molars each. Molars were bonded to zirconia blocks with a different bonding system per group. Resistance to shear forces was tested using a universal traction machine. Samples were observed under scanning electron microscopy (SEM) to determine the type of fracture. Results: Statistical analyses showed a significant influence of adhesive on the zirconia-dentin assembly's resistance to shear forces. SEM analysis showed mainly adhesive and mixed fractures. Conclusion: Dentin bonding systems without adhesive capability showed better results than self-etch systems.