The purpose of this study was to evaluate the prospective clinical results of early loading. Implants were inserted in 11 maxillae (group I, 23 implants) and 12 mandibles (group II, 19 implants). Six months after prosthetic loading, several factors were investigated. Significant differences between the primary and secondary stability were not observed in groups I and II. The primary stability in the mandible was 81.1 implant stability quotient (ISQ), which was significantly higher than the 73.3 ISQ value observed in the maxilla (P = .003). The survival rates were 100% in group I and 94.7% in group II for 9 and 10.4 months, respectively. The marginal bone loss was 0.07 mm in group I and -0.07 mm in group II. After the placement of nanostructured calcium phosphate- coated implants, excellent primary and second stability was obtained.