Domenico Cascione obtained his primary education in Bari (Italy), where he was also certified as a Dental Technologist (CDT) in 1985. From 1991 to 2004 he carried out metallurgy research becoming a specialist in dental metallurgy. From 1986 to 2004 he was the owner and director of Dental Laboratory in Bari (Italy). He is a Master Ceramist and also is specialized in metallurgy, implant work and complex esthetic rehabilitation. In 2005 he  holds a Bachelor of Science of the Dental Technology degree from the University of Southerh Illinois. From 2005 to 2008 he was Research Associate and Program Director, Advanced Training for Dental Technology at the Center for Dental Technology, the University Of Southern California Herman Ostrow School Of Dentistry. From 2009  to 2016 was a Clinical Assistant Professor and Course Director for the Advanced Dental Morphology for the Operative Dentistry Program at the University Of Southern California Ostrow School Of Dentistry. He Is a Lead Faculty Department of Restorative Dentistry – Dental Laboratory Technology Program-Division of Health Sciences at Pasadena City College. He is a Faculty/Lecturer UCLA School of Dentistry Division of Advanced Prosthodontics. He is a winner of award 2007 Judson C. Hichey in the research category in the Journal of Prosthetic Dentistry. He is an Editor in Chief of the Spectrum Dialogue magazine. He is the President of OPERART LLC dental laboratory in Santa Monica California. He is author and co-author of several articles in the literature. He is the author of the Book Symbiosis: Art & Technique.