Introduction: Complex defect situations with combined vertical and horizontal dimensions continue to be a challenge even for established augmentation procedures. New computer-assisted augmentation methods with their advantages are particularly suitable for this purpose. In the following, an augmentation of a maxillary anterior region with a combined vertical-horizontal defect which has been treated with a patient-specific CAD/CAM titanium mash based on the DAICOM data (DVT) is presented. Patient case: An otherwise healthy 30-year-old patient presented for the treatment of an endentulous space in the upper front (region 21-23) with a severe horizontal-vertical defect after tumour resection. In addition to the bony defect, there was a significant scarring in the vestibule soft tissue as a result of the pre-surgery. Based on the DICOM data, a patient-specific titanium mesh for particulate augmentation was prepared. Despite dehiscence in the healing phase, the augmentation was successful, and implantation in combination with a soft tissue management using artificial collagen matrix was performed. Keywords: CAD/CAM, Titanium mesh, augmentation, dehiscence